Download e-book for iPad: Biology of Proteoglycans (Biology of Extracellular Matrix) by Thomas N. Wight,Robert P. Mecham

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By Thomas N. Wight,Robert P. Mecham

Biology of Proteoglycans presents a consultant, yet not at all inclusive, pattern of present learn at the function of proteoglycans within the mobile biology of the extracellular matrix. The booklet is geared up into 4 components: methodological advancements; proteoglycan metabolism; proteoglycans in cartilage; and proteoglycans in "soft" tissues. It starts off with discussions of present methodological advancements that have had huge, immense impression on knowing the complexity of proteoglycan constitution. those comprise using monoclonal antibodies to probe the constitution of the protein and carbohydrate parts of proteoglycans; and reviews at the genes that code for the proteoglycan protein cores and linked proteins. this is often by way of separate chapters on quite a few facets of proteoglycan metabolism, together with the unreal pathway utilized by cells to synthesize proteoglycans containing heparin and heparan sulfate; the molecular association of alternative proteoglycans in cartilage; the position of proteoglycans and linked proteins within the calcification method in progress plate; and the rising box of proteoglycans in "soft" or noncartilagenous tissue.

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Biology of Proteoglycans (Biology of Extracellular Matrix) by Thomas N. Wight,Robert P. Mecham

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